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Open Access Article

International Research in Chinese Medicine. 2022; 2: (2) ; 18-20 ; DOI: 10.12208/j.ircm.20220019.

Analysis of TCM Syndrome Differentiation Characteristics of Uygur and Han Psoriasis
维吾尔族、汉族银屑病中医辨证特点分析

作者: 底大可 *, 帕力旦•阿布都卡的, 罗光浦, 陈永恒, 何金霞

南方医科大学皮肤病医院中西医结合皮肤科 广东广州

喀什地区第一人民医院皮肤科 新疆喀什

*通讯作者: 底大可,单位:南方医科大学皮肤病医院中西医结合皮肤科 广东广州;

发布时间: 2022-08-24 总浏览量: 697

摘要

目的 研究维、汉两族之间寻常型银屑病中医辨证特点及其与T细胞亚群相关性的异同,为下一步开发差异性治疗提供依据。方法 运用流行病学调查方法,制作观察表,对两组患者主证及兼夹证进行统计,同时运用流式细胞仪,测定CD3、CD4、CD8T淋巴细胞的数量,计算CD4/CD8的比值,并对两组患者辨证结果及实验数据进行对比分析,总结异同之处。结果 观察组血燥证、夹湿型、兼脾虚型明显高于对照组,差异具有统计学意义(P<0.05)。两组T细胞亚群CD3、CD4、CD8、CD4/CD8比较,均无明显差异(P>0.05)。结论 维、汉两族寻常型银屑病中医辨证均以血热证为主,但维族患者血燥证、夹湿型、兼脾虚型较内地汉族患者更为常见,治疗用药时需加以注意。

关键词: 维吾尔族;汉族;银屑病;辨证;T细胞亚群

Abstract

Objective To study the characteristics of TCM syndrome differentiation of psoriasis vulgaris between Uyghur and Han nationalities and their similarities and differences with their correlation with T cell subsets, so as to provide a basis for the development of differentiated treatments in the next step.
Methods The epidemiological investigation method was used to make an observation table, and the main and concurrent syndromes of the two groups of patients were counted. At the same time, flow cytometry was used to measure the number of CD3, CD4, and CD8 T lymphocytes, and the ratio of CD4/CD8 was calculated. , and compared and analyzed the syndrome differentiation results and experimental data of the two groups of patients, and summarized the similarities and differences.
Results The blood dryness syndrome, dampness type, and spleen deficiency type in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in T cell subsets CD3, CD4, CD8 and CD4/CD8 between the two groups (P>0.05).
Conclusion   The TCM syndrome differentiation of psoriasis vulgaris in Uyghur and Han nationalities is mainly based on blood heat syndrome, but blood dryness syndrome, dampness type, and spleen deficiency type are more common in Uyghur patients than in mainland Han patients, and attention should be paid when treating and using drugs.

Key words: Uygur; Han; Psoriasis; Syndrome differentiation; T cell subsets

参考文献 References

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引用本文

底大可, 帕力旦•阿布都卡的, 罗光浦, 陈永恒, 何金霞, 维吾尔族、汉族银屑病中医辨证特点分析[J]. 国际中医药研究, 2022; 2: (2) : 18-20.