An exploration and analysis of the therapeutic effect of Chaihu Shugan San prescribed by Li Qingming, a renowned veteran TCM doctor, on the syndrome of costal pain due to liver depression and qi stagnation
李卿明名老中医使用柴胡疏肝散对于胁痛肝郁气滞证型疗效探索分析

摘要

目的 探究针对胁痛肝郁气滞证型患者李卿明名老中医使用柴胡疏肝散治疗的临床效果。方法选取2024年1月-2025年6月106例乙肝胁痛（肝郁气滞证型）患者作为研究对象，通过随机数字表法展开分组处理，最终分为2组患者，均为53例，对照组应用恩替卡韦片治疗，观察组应用柴胡疏肝散治疗。结果 和对照组治疗总有效率比较，观察组显著较高（P＜0.05）。两组疼痛程度（VAS）评分对比，治疗后，VAS评分均较治疗前降低，且观察组更低（P＜0.05）。AST、ALT、TBil两组患者治疗之后均降低，观察组更低，Alb治疗后均升高，观察组更高（P<0.05）。结论 针对胁痛肝郁气滞证型患者李卿明名老中医使用柴胡疏肝散治疗的临床效果显著，可改善患者中医证候积分，有利于改善患者疼痛程度和肝功能，有利于患者取得良好预后效果，值得临床推广应用，但本研究样本少、时长短，结果存在误差，需扩大样本延长研究验证。

Abstract

Objective To explore the clinical effect of Li Qingming, a renowned traditional Chinese medicine expert, in treating patients with liver depression and qi stagnation type of costal pain using Chaihu Shugan San.
Methods The study period was from January 2024 to June 2025. A total of 106 patients with hepatitis B-induced costal pain (liver depression and qi stagnation type) were selected as the research subjects. Launch the grouping processing through the random number table method, finally, divided into 2 groups of patients were 53 cases,The control group was treated with entecavir dispersible tablets, while the observation group was treated with Chaihu Shugan San.
Results compared with the control group total effective rate, the observation group was significantly higher (P < 0.05). after treatment, the VAS score was lower, the lower and the observation group (P < 0.05).After treatment, AST, ALT, and TBil levels in both groups decreased, with the observation group having lower levels, and Alb levels increased in both groups, with the observation group having higher levels (P < 0.05).
Conclusion   The clinical effect of Li Qingming’s use of Chaihu Shugan San in treating patients with liver depression and qi stagnation type of costal pain is significant. It can improve the TCM syndrome score of patients, help improve the pain degree and liver function, and contribute to a better prognosis for patients. It is worthy of clinical promotion and application. However, this study had a small sample size and a short duration, and the results may have errors. Further studies with larger samples and longer durations are needed to verify the results.