Analysis of the therapeutic effect of Modified Yinchenhao Decoction by Li Qingming, a senior traditional Chinese medicine physician, on the syndrome of jaundice caused by liver and gallbladder damp heat
李卿明名老中医使用茵陈蒿汤加减对于黄疸肝胆湿热证型疗效探索分析

摘要

目的 探究针对黄疸肝胆湿热证型患者李卿明名老中医使用茵陈蒿汤加减的临床效果。方法 研究时间选取2023年10月-2025年4月，选取136例黄疸肝胆湿热证型患者作为研究对象，通过随机数字表法展开分组处理，最终分为2组患者，均为68例，对照组行常规药物治疗，观察组应用茵陈蒿汤加减治疗，对比恢复时间；肝功能改善情况；炎症因子指标改善情况；中医症状积分改善情况。结果 恢复时间（黄疸消退时间）观察组短于对照组（P＜0.05）。肝功能[丙氨酸转氨酶（ALT）、天冬氨酸 转氨酶（AST）、直接胆红素（DBIL）、总胆红素（TBIL）]治疗前对照组和观察组比较，差异无统计学意义（P>0.05），治疗后两组比较，均降低，观察组更低（P＜0.05）。两组中医症状积分对比，治疗前均P>0.05，中医症状积分治疗后两组均降低，观察组更低（P＜0.05）。结论 针对黄疸肝胆湿热证型患者李卿明名老中医使用茵陈蒿汤加减有利于患者临床症状消除，同时可改善患者肝功能以及中医症状积分，有利于患者取得良好预后效果，值得临床推广应用，但本研究样本少、时长短，结果存在误差，需扩大样本延长研究验证。

Abstract

Objective To explore the clinical efficacy of Li Qingming, a renowned doctor, in treating patients with jaundice and liver-chest damp-heat syndrome by using modified Yinchenhao Decoction.
Methods The study period was from October 2023 to April 2025. 136 patients with jaundice and liver-chest damp-heat syndrome were selected as the research subjects. Grouping was conducted using a random number table, and the patients were finally divided into 2 groups, each consisting of 68 cases. The control group received conventional drug treatment, while the observation group was treated with modified Yinchenhao Decoction. The recovery time, improvement of liver function, improvement of inflammatory factor indicators, and improvement of TCM symptom scores were compared.
Results The recovery time (time for jaundice to subside) of the observation group was shorter than that of the control group (P < 0.05). Before treatment, there was no statistically significant difference in liver function [alanine aminotransferase (ALT), aspartate aminotransferase (AST), direct bilirubin (DBIL), total bilirubin (TBIL)] between the control group and the observation group (P > 0.05). After treatment, both groups showed a decrease, and the observation group had a lower level (P < 0.05). The comparison of TCM symptom scores showed that before treatment, both groups had P > 0.05, and after treatment, the TCM symptom scores of both groups decreased, and the observation group had a lower score (P < 0.05).
Conclusion   The clinical efficacy of Li Qingming, a renowned doctor, in treating patients with jaundice and liver-chest damp-heat syndrome by using modified Yinchenhao Decoction is significant. It is beneficial for the elimination of clinical symptoms, and can improve liver function, inflammatory factors, and TCM symptom scores, which is conducive to achieving a good prognosis effect for patients. It is worthy of clinical promotion and application. However, this study has a small sample size and a short duration, and the results may have errors. It is necessary to expand the sample size and extend the study for verification.