摘要
目的 探究血吸虫病患者采用中药内服与中药方剂体外治疗的临床效果。方法 本研究纳入本院2023年4月-2025年4月收治血吸虫病患者，共入组86例。依照数字随机表法划分2个小组，对照组（n=43）采用常规西医治疗，观察组（n=43）在此基础上采用中药内服与自拟中药方剂（辟蛊汤）体外治疗。根据症状改善情况、临床治疗效果、不良反应评价2组治疗情况。结果 对比症状改善指标（腹痛消退时间、发热消退时间、黏液血便消退时间），观察组相较对照组均明显缩短，组间有统计学差异（P＜0.05）。对比临床疗效评估情况，观察组总有效率相较对照组明显提高，组间有统计学差异（P＜0.05）。对比不良反应情况，对照组、观察组患者无统计学差异（P＞0.05）。结论 血吸虫病患者采用中药内服与中药方剂体外治疗能进一步提升治疗效果，加快症状消退，且安全性较好。
关键词： 血吸虫病；中医方剂；不良反应
Abstract
Objective To explore the clinical effects of oral administration of traditional Chinese medicine and external treatment with traditional Chinese medicine prescriptions for patients with schistosomiasis. Methods This study included patients with schistosomiasis admitted to our hospital from April 2023 to April 2025, with a total of 86 cases enrolled. Two groups were divided according to the digital random table method. The control group (n=43) was treated with conventional Western medicine, while the observation group (n=43) was treated with internal administration of traditional Chinese medicine and external treatment with a self-designed traditional Chinese medicine prescription (Bi Gu Decoction) on this basis. The treatment conditions of the two groups were evaluated based on the improvement of symptoms, clinical treatment effects and adverse reactions. Results Compared with the symptom improvement indicators (the time for abdominal pain to subside, the time for fever to subside, and the time for mucus and bloody stool to subside), the observation group was significantly shorter than the control group, and there was a statistically significant difference between the groups (P < 0.05). By comparing the clinical efficacy assessment, the total effective rate of the observation group was significantly higher than that of the control group, and there was a statistically significant difference between the groups (P < 0.05). When comparing the adverse reactions, there was no statistically significant difference between the control group and the observation group (P > 0.05). Conclusion For patients with schistosomiasis, internal administration of traditional Chinese medicine and external treatment with traditional Chinese medicine prescriptions can further enhance the therapeutic effect, accelerate the resolution of symptoms, and have good safety.
Key words： Schistosomiasis; Traditional chinese medicine prescriptions; Adverse reactions
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