Analysis of a case of Kashin-Beck disease treated with Guizhi Shaoyao Zhimu Decoction
桂枝芍药知母汤治疗大骨节病一例分析

摘要

大骨节病是一种罕见的慢性进行性骨骼系统疾病，典型症状包括身材矮小、短趾关节畸形、步态异常，严重时可导致关节僵硬、功能障碍甚至残疾。由于发病机制复杂，全球尚未找到特效治疗[1]。中医理论体系对大骨节病治疗有独特认识和经验。桂枝芍药知母汤是中医方剂，源于医圣张仲景的《金匮要略》，其核心功效在于温阳散寒、祛风除湿。该方剂以温热药物为主，旨在驱散体内寒湿之邪，同时调和营卫气血，以达到缓解关节疼痛、改善关节功能目的[3]。本文将通过1例典型的大骨节病患者如何运用桂枝芍药知母汤治疗的实际案例分析，探究该治疗方法的效果，现报告如下。

Abstract

Kashin-Beck disease is a rare, chronic, progressive skeletal disease with typical symptoms including short stature, short toe joint deformities, and abnormal gait. In severe cases, it can lead to joint stiffness, dysfunction, and even disability. Due to the complex pathogenesis, no specific treatment has been found in the world [1]. The theoretical system of traditional Chinese medicine has a unique understanding and experience in the treatment of Kashin-Beck disease. Guizhi Shaoyao Zhimu Decoction is a traditional Chinese medicine prescription that originated from the "Golden Chamber" by the medical saint Zhang Zhongjing. Its core efficacy is to warm the yang and dispel cold, and to dispel wind and dampness. The prescription is mainly composed of warm and hot drugs, aiming to dispel cold and dampness in the body, while harmonizing the nutrient and defensive qi and blood, so as to relieve joint pain and improve joint function [3]. This article will explore the effect of this treatment method through an actual case analysis of a typical Kashin-Beck disease patient using Guizhi Shaoyao Zhimu Decoction. The report is as follows.