The improvement effect of modified Ganlu Disinfection Pill combined with anti infective drugs in the treatment of damp heat lung type bacterial pneumonia and mycoplasma pneumoniaon inflammatory response
甘露消毒丹加减治疗配合抗感染药物治疗湿热蕴肺型细菌性肺炎和支原体肺炎对炎症反应的改善作用

摘要

目的 观察分析对湿热蕴肺型细菌性肺炎和支原体肺炎患者实施甘露消毒丹加减治疗配合抗感染药物治疗的临床效果和应用价值。方法 采用回顾性研究方法，选择院内就诊的60例湿热蕴肺型细菌性肺炎和支原体肺炎患者（样本纳入例数：60例；样本纳入时间：2022年5月至2023年5月），以随机摸球为基础分组方式，分为对照、实验两个小组，观察例数高度一致。分别实施抗感染药物治疗，甘露消毒丹加减治疗+抗感染药物治疗。收集分析治疗效果。结果 与对照组相比，实验组治疗后炎症因子水平（IL-6/IL -4/hs-CRP/TNF -α）更低，治疗后的炎症持续时间（高热/咳嗽/痰中带血）更短，肺功能指标（FVC、FEV1、FEV1/FVC）更高（P<0.05）。结论 甘露消毒丹加减治疗配合抗感染药物治疗可以有效抑制湿热蕴肺型细菌性肺炎和支原体肺炎患者炎症反应，促进症状改善，促进肺功能恢复，有较高应用价值。

Abstract

Objective To observe and analyze the clinical effect and application value of Ganlu Sanitizing Dan combined with anti-infective drugs in the treatment of patients with damp-heat pulmonary bacterial pneumonia and mycoplasma pneumonia.
Methods A retrospective study was carried out to select 60 patients with damp-heat pneumopneumonic bacterial pneumonia and mycoplasma pneumonia (sample number: 60 cases; Sample inclusion time: May 2022 to May 2023) was divided into control and experimental groups based on random ball touching, and the number of observed cases was highly consistent. Anti-infective drug treatment, manna disinfection Dan plus plus plus anti-infective drug treatment were respectively implemented. The therapeutic effect was collected and analyzed.
Results Compared with the control group, the experimental group had lower levels of inflammatory factors (IL-6/ IL-4 /hs-CRP/ TNF-α), shorter duration of inflammation (high fever/cough/blood in sputum), and higher lung function indexes (FVC, FEV1, FEV1/FVC) after treatment (P<0.05).
Conclusion   The treatment of Ganlu Sanijian combined with anti-infective drugs can effectively inhibit the inflammatory response of patients with damp-heat pneumopneumonic bacterial pneumonia and mycoplasma pneumonia, promote the improvement of symptoms, and promote the recovery of lung function, which has high application value.