摘要
目的 探究苓桂术甘汤联合沙库巴曲缬沙坦纳用于治疗左室射血分数保留心力衰竭的临床疗效。方法 对2023年1月~12月在本院接受治疗的左室射血分数保留心力衰竭患者作为研究对象，从中随机抽选出100例患者，按照简单随机法将这100例患者分为对照组与观察组，每组各50例病患。对照组——采用沙库巴曲缬沙坦纳进行治疗，观察组患者在对照组的基础上加以苓桂术甘汤进行治疗。对比两组患者治疗前后血清炎症因子、心脏参数、心功能指标。结果 治疗前两组左室射血分数保留心力衰竭患者的血清炎症因子、心功能指标、心脏参数指标对比均无显著差异性：P＞0.05；治疗后观察组患者的血清炎症因子、心功能指标、心脏参数改善程度均优于对照组，数据比较存在统计学意义（P＜0.05）。结论 苓桂术甘汤联合沙库巴曲缬沙坦钠片用于治疗左室射血分数保留心力衰竭患者中，能够明显改善患者的心功能指标，显著改善心脏不良构建。
关键词： 苓桂术甘汤；沙库巴曲缬沙坦钠；左室射血分数；心力衰竭；临床疗效
Abstract
Objective To explore the clinical efficacy of Linggui Zhugan Decoction combined with Shakubatryl valsartana in the treatment of left ventricular ejection fraction preserving heart failure. Methods From January to December 2023, patients with heart failure with left ventricular ejection fraction preservation were selected as the study objects. 100 patients were randomly selected and divided into control group and observation group according to simple randomization method, with 50 patients in each group. The control group was treated with sakubactril and valsartana, and the observation group was treated with Linggui Zhugan Decoction on the basis of the control group. Serum inflammatory factors, cardiac parameters and cardiac function indexes were compared between the two groups before and after treatment. Results Before treatment, there were no significant differences in serum inflammatory factors, cardiac function indexes and cardiac parameters in patients with left ventricular ejection fraction preservation heart failure between the two groups: P > 0.05; After treatment, the improvement of serum inflammatory factors, cardiac function indexes and cardiac parameters in the observation group was better than that in the control group, with statistical significance (P < 0.05). Conclusion Linggui Zhugan Decoction combined with Shakubatryl valsartan sodium tablets can significantly improve the cardiac function indexes and improve the cardiac dysfunction in patients with left ventricular ejection fraction preservation heart failure.
Key words： Sweet decoction; Shakubatrivalsartan sodium; Left ventricular ejection fraction; Heart failure; Clinical efficacy
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